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The H5N1 strain of bird flu that has killed 241 people is not the only one that could trigger a pandemic, according to research in America. A few H7 strains of the flu virus have started to evolve some of the traits they would need to infect people easily, scientists have discovered.

The findings, from a team led by Terrence Tumpey, of the US Centres for Disease Control and Prevention (CDC) in Atlanta, show that while there is no immediate indication that H7 flu is about to acquire potentially damaging mutations, it is critical that global surveillance and research covers this virus class as well as the more obvious H5N1, scientists said.

The H5N1 strain has been regarded as the most deadly strain since it appeared in Asia in 2003. Although it has a death rate of more than 60 per cent, it has not yet acquired the ability to move from person to person, which would be a prerequisite for a pandemic. ....
 

Each of the three flu pandemics of the last century was caused by a humanised strain of flu. The Spanish Flu of 1918-19, which killed up to 40 million people, was caused by an H1N1 virus. The 1957-58 Asian Flu was caused by an H2N2 strain, and the 1968-69 Hong Kong Flu by an H3N2 strain.

Plague proportions

— Flu strains are categorised according to two key proteins, called haemagglutinin (H) and neuraminidase (N)

— The strain currently endemic in birds in many parts of the world, particularly in Asia, is H5N1

A first solid case of human-to-human transmission, between a father and son in China, was reported last month

— Other avian strains of flu that could prove threatening to people include the H7 family, the subject of the new research

— Defences are largely reliant on antiviral drugs, particularly Tamiflu. The UK has ordered sufficient courses to cover 30 million people

The Government says that up to 750,000 people could die in a pandemic, though a figure of 150,000-375,000 is thought likelier

Source: Times Database

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